Japanese encephalitis (JE) is a viral infection transmitted by mosquitoes. Here's an overview of its symptoms, diagnosis, and treatment.
Fever: Typically the initial symptom, often accompanied by headache and malaise.
Encephalitis: In severe cases, inflammation of the brain (encephalitis) can occur, leading to symptoms such as:
Severe Headache
Confusion
Seizures
Stiff Neck
Disorientation
Tremors
Muscle Weakness
Paralysis
Neurological Symptoms: These may include movement disorders, focal neurological deficits, and altered consciousness.
In some cases: JE can cause long-term neurological complications or death.
Supportive Care: There is no specific antiviral treatment for JE. Treatment focuses on managing symptoms and providing supportive care, which may include:
Fever Reduction: With antipyretic medications.
Pain Management: With analgesics.
Intravenous Fluids: To maintain hydration.
Mechanical Ventilation: If respiratory function is compromised.
Anticonvulsants: To control seizures.
Prevention:
Vaccination: JE vaccine is available and recommended for travelers to endemic regions and for individuals living in or visiting areas with ongoing JE transmission.
Mosquito Avoidance: Measures to prevent mosquito bites, such as using insect repellents, wearing protective clothing, and using bed nets.
Clinical Evaluation: Based on symptoms and travel history (JE is prevalent in certain regions of Asia).
Laboratory Tests:
Blood Tests: To detect antibodies against the JE virus or viral RNA.
Cerebrospinal Fluid (CSF) Analysis: Elevated white blood cell count and protein levels may indicate inflammation of the brain.
Imaging Studies: MRI or CT scans of the brain may show abnormalities consistent with encephalitis.