Health A-Z

IgA nephropathy, also known as Berger's disease, is a kidney disorder characterized by the accumulation of a protein called immunoglobulin A (IgA) in the kidneys. This can lead to inflammation and damage to the kidney tissues. Here's an overview of symptoms, diagnosis, and treatment.

1. Blood in Urine (Hematuria): This is the most common symptom, often initially noticed during an episode of a respiratory or gastrointestinal infection.
2. Proteinuria: Protein in the urine, though sometimes this might not be noticeable.
3. High Blood Pressure: Due to kidney damage, blood pressure may rise.
4. Swelling (Edema): Particularly in the ankles and around the eyes.

1. Blood Pressure Control: ACE inhibitors or angiotensin II receptor blockers (ARBs) are commonly used to control blood pressure and reduce proteinuria.
2. Immunosuppressive Therapy: In some cases, medications like corticosteroids or immunosuppressants may be prescribed to reduce inflammation and slow down the progression of kidney damage.
3. Dietary Changes: Reducing salt intake and limiting protein may help manage symptoms.
4. Monitoring and Follow-Up: Regular check-ups with a nephrologist are important to monitor kidney function and adjust treatment as necessary.
5. Treatment of Complications: Addressing complications such as infections or fluid retention promptly is crucial.

1. Urinalysis: Detects the presence of blood and protein in the urine.
2. Blood Tests: To assess kidney function and look for signs of inflammation.
3. Kidney Biopsy: The definitive test, where a small sample of kidney tissue is examined under a microscope to confirm IgA nephropathy and assess the extent of kidney damage.